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吴益东

文章作者: 档案馆 发布日期: 2015-12-07

    吴益东,教授,博士生导师。1994年获得南京农业大学昆虫专业博士学位,2000年晋升教授。先后在英国Rothamsted研究所、法国CIRAD和澳大利亚墨尔本大学遗传系进行2年合作研究。目前担任Pest Management Science副编辑和Insect Science编委。

    长期从事农业害虫抗药性研究,主持和承担国家自然科学基金、863、转基因生物品种培育重大科研专项、行业科技专项等课题15项。在PNAS, Evolutionary Applications, Insect Biochemistry and Molecular Biology, Applied and Environmental Microbiolgy,Pest Management Science等重要国际学术刊物发表SCI论文40余篇。 

    获教育部科技进步奖二等奖1项(1999,第1完成人)、教育部自然科学奖二等奖1项(2006,第2完成人)、国家科学技术进步奖二等奖1项(2010,第3完成人)。先后获得教育部首届高校青年教师奖(1999)、江苏省第六届青年科技奖(2000)、江苏省“333高层次人才培养工程”首批中青年科技领军人才(2007)、“新世纪百千万人才工程”国家级人选(2009)。                            

研究方向

昆虫分子毒理,害虫抗药性,Bt作物抗性监测与治理

研究课题

* 重要鳞翅目害虫抗药性监测及治理技术研究与示范,公益性(农业)行业科研专项经费项目,2012-2016.

* 小菜蛾抗药性监测与机理,公益性(农业)行业科研专项经费项目,2011-2015.

* 棉铃虫对Bt棉花抗性频率监测与风险管理,转基因生物新品种培育重大专项,2011-2015.

* 棉铃虫Cry1Ac抗性显性遗传品系的抗性机理及适合度,国家自然科学基金,2011-2013.

* Bt毒素Cry1Ac与棉铃虫中肠受体钙粘蛋白和氨肽酶的互作,国家自然科学基金,2009-2011.

* 棉铃虫对Bt毒素抗性的高通量分子检测技术,863项目,2007-2010.

* 杀虫药剂诱导害虫再猖獗的机制,973项目子课题骨干,2006-2010.

* 棉铃虫田间种群钙粘蛋白基因变异与对Bt毒素抗性的关系,国家自然科学基金,2006-2008.

* 用RNA干涉技术研究棉铃虫细胞色素P450基因与抗药性的关系,国家自然科学基金,2005-2007.

* 小规模棉花生产体系棉铃虫的可持续控制,国际合作项目(CFC/ICAC/14),2000-2005.

* BT棉在中国的农业和环境适合性评估,欧盟第五框架国际合作项目,2001-2005.

* 棉铃虫细胞色素P450同工酶的纯化及抗性基因检测,国家自然科学基金项目,1998-2000.

* 棉铃虫细胞色素P450与抗药性的关系,国家自然科学基金项目,1995-1997.  

研究成果

(*通讯作者)

2013年:

Lin Jin, Yiyun Wei, Lei Zhang, Yihua Yang, Bruce E. Tabashnik, and Yidong Wu*. 2013. Dominant resistance to Bt cotton and minor cross-resistance to Bt toxin Cry2Ab in cotton bollworm from China. Evolutionary Applications 6(8):1222-1235.

Haonan Zhang,  Minyi Tang, Fan Yang, Yihua Yang, and Yidong Wu*.  2013. DNA-based screening for an intracellular cadherin mutation conferring non-recessive Cry1Ac resistance in field populations of Helicoverpa armigera. Pesticide Biochemistry and Physiology 107(1): 148-152.

Xingliang Wang, S. K. Khakame, Cao Ye, Yihua Yang, and Yidong Wu*. 2013. Characterisation of field-evolved resistance to chlorantraniliprole in the diamondback moth, Plutella xylostella, from China. Pest Management Science 69(5): 661-665.

Yihua Yang, Yapeng Li, and Yidong Wu*. 2013. Current status of insecticide resistance in Helicoverpa armigera after 15 years of Bt cotton planting in China. Journal of Economic Entomology 106(1): 375-381.

S. K. Khakame, Xingliang Wang, and Yidong Wu*. 2013. Baseline toxicity of metaflumizone and lack of cross resistance between indoxacarb and metaflumizone in diamondback moth (Lepidoptera: Plutellidae). Journal of Economic Entomology 106(3): 1423-1429.

Wunan Che, Tan Shi, Yidong Wu, and Yihua Yang*. 2013. Insecticide resistance status of field populations of Spodoptera exigua (Lepidoptera: Noctuidae) from China. Journal of Economic Entomology 106(4): 1855-1862.

J. G. Oakeshott*, C. A. Farnsworth, P. D. East, C. Scott, Yangchun Han, Yidong Wu, and R. J. Russell. 2013. How many genetic options for evolving insecticide resistance in heliothine and spodopteran pests? Pest Management Science 69(8): 889-896.

2012年:

Haonan Zhang, Wen Tian, Jing Zhao, Lin Jin, Jun Yang, Chunhui Liu, Yihua Yang, Shuwen Wu, Kongming Wu, Jinjie Cui, Bruce E. Tabashnik, and Yidong Wu*. 2012. Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from China. PNAS 109(26): 10275-10280. 

Haonan Zhang, Shuwen Wu, Yihua Yang, B. E. Tabashnik, and Yidong Wu*. 2012. Non-Recessive Bt Toxin Resistance Conferred by an Intracellular Cadherin Mutation in Field-Selected Populations of Cotton Bollworm. PLoS ONE 7(12): e53418.

Xingliang Wang and Yidong Wu*. 2012. High Levels of Resistance to Chlorantraniliprole Evolved in Field Populations of Plutella xylostella. Journal of Economic Entomology 105(3): 1019-1023. 

Xingliang Wang, Shuwen Wu, Yihua Yang, and Yidong Wu*. 2012. Molecular cloning, characterization and mRNA expression of a ryanodine receptor gene from diamondback moth, Plutella xylostella. Pesticide Biochemistry and Physiology, 102(3):204-212.

Yangchun Han, Shuwen Wu, Yapeng Li, Jian-Wei Liu, Peter M. Campbell, Claire Farnsworth, Colin Scott, Robyn J. Russell, John G. Oakeshott, and Yidong Wu*. 2012. Proteomic and molecular analyses of esterases associated with monocrotophos resistance in Helicoverpa armigera. Pesticide Biochemistry and Physiology 104(3):243-251.

B. E. Tabashnik*, Kongming Wu, and Yidong Wu. 2012. Early detection of field-evolved resistance to Bt cotton in China: Cotton bollworm and pink bollworm. Journal of Invertebrate Pathology 110(3): 301-306.

2011年:

Haonan Zhang, Wei Yin, Jing Zhao, Lin Jin, Yihua Yang, Shuwen Wu, Bruce E. Tabashnik, and Yidong Wu*. 2011. Early Warning of Cotton Bollworm Resistance Associated with Intensive Planting of Bt Cotton in China. PLoS ONE 6(8): e22874.  

Shuwen Wu, Yihua Yang, Guorui Yuan, Peter M. Campbell, Mark G. Teese, Robyn J. Russell, John G. Oakeshott, and Yidong Wu*. 2011. Overexpressed esterases in a fenvalerate resistant strain of the cotton bollworm, Helicoverpa armigera. Insect Biochemistry and Molecular Biology 41(1): 14-21.

Tabashnik BE*,Huang FN,Ghimire MN,Leonard BR,Siegfried BD,Rangasamy M,Yang Yajun,Wu Yidong,Gahan LJ,Heckel DG,Bravo A,Soberon M. 2011. Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance. Nature Biotechology 29(12): 1128-1131.

2010年:

Zhenyu Wang, Haifei Yan, Yihua Yang, and Yidong Wu*. 2010. Biotype and insecticide resistance status of the whitefly Bemisia tabaci from China. Pest Management Science 66(12): 1360-1366.

Guorui Yuan, Weiyue Gao, Yihua Yang, and Yidong Wu*. 2010. Molecular cloning, genomic structure and genetic mapping of two Rdl-orthologous genes of GABA receptors in the diamondback moth, Plutella xylostella. Achives of Insect Biochemistry and Physiology 74(2): 81-90

Youjing Gong, Chongli Wang, Yihua Yang, Shuwen Wu, and Yidong Wu*. 2010. Characterization of resistance to Bacillus thuringiensis toxin Cry1Ac in Plutella xylostella from China. Journal of Invertebrate Pathology 104(2): 90-96.

Xingliang Wang, Xiangyong Li, Aidong Shen, and Yidong Wu*. 2010. Baseline susceptibility of the diamondback moth (Lepidoptera: Plutellidae) to chlorantraniliprole in China. Journal of Economic Entomology 103(3): 843-848.

Xin Pu, Yihua Yang, Shuwen Wu, and Yidong Wu*. 2010. Characterization of abamectin resistance in a field-evolved multi-resistant population of Plutella xylostella. Pest Management Science 66(4): 371-378.

Jing Zhao, Lin Jin, Yihua Yang, and Yidong Wu*. 2010. Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicoverpa armigera. Insect Biochemistry and Molecular Biology 40(2): 113-118.

Cun-Zheng Zhang, Zhi-Yong Zhang, Xian-Jin Liu, Wayne Jiang, and Yi-Dong Wu*. 2010. Dissipation and environmental fate of herbicide H-9201 in carrot plantings under field conditions. Food Chemistry 119: 874-879.

2009年:

Zhenyu Wang, Mingde Yao, and Yidong Wu*. 2009. Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B biotype Bemisia tabaci. Pest Management Science 65(11): 1189-1194.

Yidong Wu*, Jean-Michel Vassal, Monica Royer, and Isabelle Pieretti. 2009. A single linkage group confers dominant resistance to Bacillus thuringiensis δ-endotoxin Cry1Ac in Helicoverpa armigera. Journal of Applied Entomology 133(5): 375-380. 

Yihua Yang, Yajun Yang, Weiyue Gao, Jingjie Guo, Yanhong Wu, and Yidong Wu*. 2009. Introgression of a disrupted cadherin gene enables susceptible Helicoverpa armigera to obtain resistance to Bacillus thuringiensis toxin Cry1Ac. Bulletin of Entomological Research 99(2): 175-181.

2004-2008年:

Yihua Yang, Lina Yue, Song Chen, and Yidong Wu*. 2008. Functional expression of Helicoverpa armigera CYP9A12 and CYP9A14 in Saccharomyces cerevisiae. Pesticide Biochemistry and Physiology 92(2): 101-105.

Xinjun Xu and Yidong Wu*. 2008. Disruption of Ha_BtR alters binding of Bacillus thuringiensis δ-endotoxin Cry1Ac to midgut BBMVs of Helicoverpa armigera. Journal of Invertebrate Pathology 97(1): 27-32.

Yajun Yang, Haiyan Chen, Yidong Wu*, Yihua Yang, and Shuwen Wu. 2007. Mutated cadherin alleles from a field population of Helicoverpa armigera confer resistance to Bacillus thuringiensis toxin Cry1Ac. Applied and Environmental Microbiology 73(21): 6939-6944.

Lihua Wang and Yidong Wu*. 2007. Cross-resistance and biochemical mechanisms of abamectin resistance in the B-type Bemisia tabaci. Journal of Applied Entomology 131(2): 98-103.

Yihua Yang, Song Chen, Shuwen Wu, Lina Yue, and Yidong Wu*. 2006. Constitutive overexpression of multiple cytochrome P450 genes associated with pyrethroid resistance in Helicoverpa armigera. Journal of Economic Entomology 99(5): 1784-1789. 

Yajun Yang, Haiyan Chen, Shuwen Wu, Yihua Yang, Xinjun Xu, and Yidong Wu*. 2006. Identification and molecular detection of a deletion mutation responsible for a truncated cadherin of Helicoverpa armigera. Insect Biochemistry and Molecular Biology 36(9): 735-740.

Ageng Li, Yihua Yang, Shuwen Wu, Chao Li, and Yidong Wu*. 2006. Investigation of resistance mechanisms to fipronil in the diamondback moth (Lepidoptera: Yponomeutidae). Journal of Economic Entomology 99(3): 914-919.

Xinjun Xu, Liangying Yu, and Yidong Wu*. 2005. Disruption of a cadherin gene associated with resistance to Cry1Ac δ-endotoxin of Bacillus thuringiensis in Helicoverpa armigera. Applied and Environmental Microbiology 71(2): 948-954.

Song Chen, Yihua Yang, and Yidong Wu*. 2005. Correlation between fenvalerate resistance and cytochrome P450 mediated O-demethylation activity in Helicoverpa armigera (Lepidoptera: Noctuidae). Journal of Economic Entomology 98(3): 943-946.

Enhui Yang, Yihua Yang, Shuwen Wu, and Yidong Wu*. 2005. Relative contribution of detoxifying enzymes to pyrethroid resistance in a resistant strain of Helicoverpa armigera. Journal of Applied Entomology 129(9): 521-525.

Yihua Yang, Yidong Wu*, Song Chen, G. J. Devine, I. Denholm, P. Jewess, and G. D. Moores. 2004. The involvement of microsomal oxidases in pyrethroid resistance in Helicoverpa armigera from Asia. Insect Biochemistry and Molecular Biology 34(8): 763-773.

摘自http://plant.njau.edu.cn/html/szdw/kcxx/js/2014/09/18/52b217d9-4f3b-4d9b-9bc6-5c90a444c998.html