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张正光

文章作者: 档案馆 发布日期: 2015-12-07

    张正光,博士,教授,博士生导师。国家杰出青年科学基金获得者(2013年)、江苏省特聘教授。

2002年于南京农业大学植物病理学专业获博士学位。2000.4—2000.12在蛋白质工程及植物基因工程国家重点实验室从事植物对疫霉菌非寄主抗性分子机制研究;2005-2006  美国路易丝安娜州立大学健康研究中心儿童研究所从事真菌分子生物学与信号传导博士后研究。现致力于稻瘟病菌分子生物学及植物与病原菌互作分子机制研究。在国内外发表研究论文70余篇,其中SCI论文40多篇。近5年以通讯作者在PLoS Pathogens、New Phytologist、MPMI、JXB和PCE等刊物上发表研究论文20篇,总影响因子近100。

先后入选南京农业大学“133人才工程”学术带头人、江苏省“青蓝工程”优秀骨干教师、教育部新世纪优秀人才和江苏省333人才第三层次,2011年获江苏省青年科技奖。国际期刊PLoS One和Current Genetics学术编委。             

研究方向

1. 稻瘟病菌的致病分子机制研究

2. 植物对疫霉菌的非寄主抗性分子机制研究

研究课题

主持的科研项目

1. 2004.1-2006.12 疫霉菌诱导非寄主植物过敏性反应激发子基因的克隆.   国家自然科学基金项目(30300228),

2. 2005.1-2007.12 疫霉菌不同激发子诱导非寄主抗性中信号分子作用机制比较分析.  国家自然科学基金项目(30471123),

3. 2005.6-2007.12 疫霉菌激发子诱导非寄主抗性中关键基因的克隆及功能分析. 江苏省创新人才基金项目(BK2005421),

4. 2006.10-2011.9 农作物重大病害成灾机理及控制的基础研究. 国家“973”计划子课题,

5. 2008-2010 教育部新世纪人才支持计划(NCT-07-0442). 

6. 2008.3-2010.10 利用病毒诱导基因沉默技术高通量筛选非寄主抗性基因及其应用. 国家“863”计划(2008AA10Z410)

7. 2008.1-2011.12 疫霉菌激发子诱发的调控过敏性细胞死亡的基因克隆及功能分析. 国家自然科学基金项目(30871605)

8. 2011.1-2013.12 由NbALY916介导的信号途径调控疫霉菌激发子诱发的过敏性细胞死亡分子机制研究. 国家自然科学基金项目(31071645)

9. 2013.1-2016.12 稻瘟病菌转录因子MoAp1介导的基因调控网络生物学功能解析. 国家自然科学基金项目(31271998)

10.国家杰出青年科学基金项目,植物病理学(2014.1-2017.12)

参加科研项目5项.

研究成果

发表的代表性论文

1.Chen Y, Zuo RF, Zhang HF, Sun Y, Zheng XB, Zhang ZG*. MoLys2 is necessary for growth, conidiogenesis, lysine biosynthesis and pathogenicity of Magnaporthe oryzae. Fungal Genetics and Biology, 2014,67: 51-57(*Corresponding author)(If 3.7)

2.Teng WJ, Zhang HJ, Wang W, Li DQ, Wang MF, Liu JW, Zhang HF, Zheng XB, Zhang ZG*. ALY proteins participate in multifaceted Nep1Mo-triggered responses in Nicotiana benthamiana and Arabidopsis thaliana. Journal of Experimental Botany, 2014 (Accepted) (*Corresponding author) (IF5.2)

3.Zhang HF, Zhao Q, Guo XX, Guo M, Qi ZQ, Tang W, Ye WW, Zheng XB, Wang P, Zhang ZG*. Pleiotropic function of the putative Zinc-finger protein MoMsn2 in Magnaporthe oryzae. Molecular Plant-Microbe Interaction, 2014, 27: 446-460 (*Corresponding author) (IF 4.41)

4.hen Y, Zhai S, Zhang HF, Zuo RF, Wang JM, Guo M, Zheng XB, Wang P, Zhang ZG*. Shared and distinct functions of two Gti1/Pac2 family proteins in growth, morphogenesis, and pathogenicity of Magnaporthe oryzae. Environmental Microbiology, 2014,16(3): 788-801 (*Corresponding author) (IF 5.71)

5.Du Y, Zhang HF, Hong L, Wang JW, Zheng XB, Zhang ZG*. Acetolactate synthases MoIlv2 and MoIlv6 are required for infection-related morphogenesis in Magnaporthe oryzae. Molecular Plant Pathology, 2013, 14(9): 870-884  (*Corresponding author) (IF 3.71)

6.Wang JM, Du Y, Zhang HF, Zhou C, Qi ZQ, Zheng XB, Wang P, Zhang ZG*. The actin-regulating kinase homologue MoArk1 plays a pleiotropic function in Magnaporthe oryzae. Molecular Plant Pathology, 2013(5), 14: 470-482  (*Corresponding author) (IF 3.71)

7.Qi ZQ, Wang Q, Dou XY, Wang W, Zhao Q, Lv RL, Zhang HF, Zheng XB, Wang P, Zhang ZG*. MoSwi6, an MAP kinase Mps1 interacting APSES family transcription factor, is required for hyphal and conidial morphogenesis, appressorial function, and pathogenicity of Magnaporthe oryzae. Molecular Plant Pathology, 2012, 13: 677-689 (*Corresponding author) (IF 3.71)

8.Zhang HF, Tang W, Liu KY, Huang Q, Zhang X, Yan X, Chen Y, Wang JS, Qi ZQ, Wang ZY, Zheng XB, Wang P, Zhang ZG*. Eight RGS and RGS-like proteins orchestrate growth, differentiation, and pathogenicity of Magnaporthe oryzae. PLoS Pathogens, 2011,7:e1002450 (*Corresponding author) (IF 9.08)

9.Zhang HJ, Wang MF, Wang W, Li DQ, Huang Q, Wang YC, Zheng XB, Zhang ZG*. Silencing of G proteins uncovers diversified plant responses when challenged by three elicitors in Nicotiana benthamiana. Plant Cell & Environment, 2012, 35: 72-85 (*Corresponding author) (IF 5.15)

10.Zhang LS, Lv RL, Dou XY, Qi ZQ, Hua CL, Zhang HF, Wang ZY, Zheng XB, Zhang ZG*. The function of MoGlk1 in integration of glucose and ammonium utilization in Magnaporthe oryzae. PLoS ONE, 2011, 6(7): e22809 (*Corresponding author) (IF 4.41)

11.Zhang HF, Liu KY, Zhang X, Tang W, Wang JS, Guo M, Zhao Q, Zheng XB, Wang P, Zhang ZG*. Two phosphodiesterase genes, PDEL and PDEH, regulate development and pathogenicity by modulating intracellular cyclic AMP levels in Magnaporthe oryzae. PLoS One, 2011, 6(2): e17241 (*Corresponding author) (IF 4.41)

12.Guo M, Chen Y, Du Y, Dong YH, Guo W, Zhai S, Zhang HF, Zhang ZG*, Wang YC, Wang P, Zheng XB. The bZIP transcription factor MoAP1 mediates the oxidative stress response and is crucial for pathogenicity of the rice blast fungus Magnaporthe oryzae. PLoS Pathogens, 2011, 7(2):e1001302 (*Corresponding author) (IF 9.08) 

13.Dou XY, Wang Q, Qi ZQ, Song WW, Wang W, Guo M, Zhang HF, Zhang ZG*, Wang P, Zheng XB. MoVam7, a conserved SNARE component involved in vacuole assembly, is required for growth, endocytosis, chitin distribution, ROS accumulation, and pathogenesis of Magnaporthe oryzae. PLoS One, 2011, 6(1): e16439 (*Corresponding author) (IF 4.41) 

14.Dong S, Yin W, Kong G, Yang X, Qutob D, Chen Q, Kale S.D, Sui Y, Zhang Z, Dou D, Zheng X, Gijzen M, Tyler B, Wang Y*,.Phytophthora sojae avirulence effector Avr3b is a secreted NADH and ADP-ribose pyrophosphorylase that modulates plant immunity. PLoS Pathogens, 2011, 7(11):e1002353.

15.Wang Q, Han C, Ferreira AO, Yu X, Ye W, Tripathy S, Kale SD, Gu B, Sheng Y, Sui Y, Wang X, Zhang Z, Cheng B, Dong S, Shan W, Zheng X, Dou D, Tyler BM, Wang Y*. Transcriptional Programming and Functional Interactions within the Phytophthora sojae RXLR Effector Repertoire. Plant Cell. 2011, 23(6):2064-86.

16.Song WW, Dou XY, Qi ZQ, Wang Q, Zhang X, Zhang HF, Guo M, Dong SM, Zhang ZG*, Wang P, Zheng XB. R-SNARE homolog MoSec22 is required for conidiogenesis, cell wall integrity, and pathogenesis of Magnaporthe oryzae. PLoS One, 2010, 5: e13193 (*Corresponding author) (IF 4.41) 

17.Zhang HF, Liu KY, Zhang X, Song WW, Dong YH, Zhao Q, Guo M, Zheng XB, Zhang ZG*. A two-component histidine kinase, SLN1, is required for cell wall integrity and pathogenicity of the rice blast fungus, Magnaporthe oryzae. Current Genetics, 2010 56:517–528 (*Corresponding author) IF 2.32) 

18.Zhang HJ, Dong SM, Wang MF, Wang W, Song WW, Dou XY, Zheng XB, and Zhang ZG*. The role of vacuolar processing enzyme (VPE) from Nicotiana benthamiana in elicitor-triggered hypersensitive response and stomatal closure. Journal of Experimental Botany, 2010, 61: 3799-3812 (*Corresponding author) (IF 4.82) 

19.Guo M, Guo W, Chen Y, Dong SM, Zhang X, Song WW, Wang W, Wang Q, Lv RL, Zhang ZG*, Wang YC, Zheng XB. The bZIP transcription factor Moatf1 mediates oxidative stress responses and is necessary for full virulence of the rice blast fungus Magnaporthe oryzae. Molecular Plant-Microbe Interaction, 2010, 23: 1053-1068 (*Corresponding author) (IF 4.4) 

20.Zhang HJ, Fang Q, Zhang ZG*, Wang YC, Zheng XB. The role of respiratory burst oxidase homologs in elicitor-induced stomatal closure and hypersensitive response in Nicotiana benthamiana. Journal of Experimental Botany, 2009, 60: 3109-3122 (*Corresponding author) (IF 4.82) 

21.Zhang HF, Zhao Q, Liu KY, Zhang ZG*, Wang YC, Zheng XB. MgCRZ1, a transcription factor of Magnaporthe grisea, controls growth, development and is involved in full virulence. FEMS Microbiology Letter, 2009, 293: 160–169 (*Corresponding author) (IF 2.27) 

22.Gan YZ, Zhang LS, Zhang ZG*, Dong SM, Li J, Wang YC*, Zheng XB. The LCB2 subunit of the sphingolip biosynthesis enzyme serine palmitoyltransferase can function as an attenuator of the hypersensitive response and Bax-induced cell death. New Phytologist, 2009, 181: 127-146 (*Corresponding author) (IF 6.52) 

23.Li L, Shen G, Zhang ZG, Wang YL, Thompson JK, Wang P. Canonical heterotrimeric G proteins regulating mating and virulence of Cryptococcus neoformans. Molecular Biolgoy of the Cell. 2007, 18: 4201-4209 (IF 6.56) 

24.Zhang ZG, Li YQ, Wang YC, Zheng XB. Molecular Detection of Phytophthora capsici in infected plant tissues, soil and water. Plant Pathology, 2006, 55: 770-775 (IF 2.01) 

25.Wang ZY, Wang YC, Chen XR, Shen G, Zhang ZG, Zheng XB. Differential screening reveals genes differentially expressed in low- and high-virulence near-isogenic Phytophthora sojae lines. Fungal Genetics and Biology, 2006, 43: 826-839 (IF 3.43) 

26.Zhang ZG, Zhang JY, Wang YC and Zheng XB. Molecular detection of Fusarium oxysporum f.sp. niveum and Mycosphaerella melonis in infected plant tissues and soil. FEMS Microbiology Letter, 2005, 249: 39-47 (IF 2.27)

获得荣誉

1. 2005年获教育部自然科学二等奖,疫霉菌多样性及其产生机制(3/7)。

2. 2007年获教育部科学技术进步一等奖,重要植物病原生物快速分子检测技术研究及其应用(5/9)

3. 2011年获江苏省青年科技奖

社会兼职

《PLoS One》编委

《Current Genetics》编委 

《植物学研究》共同主编   

江苏省植物病理学会理事

摘自http://plant.njau.edu.cn/html/szdw/zwblxx/js/2014/09/17/c06d6467-a1ad-43f0-aaa4-52fc2795ad99.html